Biomarkers of bacterial vaginosis: analytical review
Abstract
The microbiome of healthy female genital tracts is dominated by bacteria that produce lactic acid and hydrogen peroxide, which contribute to a low phlewel and thereby provide protection against infectious diseases. Changes in the bacterial composition of the vaginal microbiome contribute to the development of bacterial vaginosis. Pregnant women with bacterial vaginosis may develop chorioamnionitis, premature rupture of membranes, and preterm labor. Clinical and microscopic methods and traditionally used to diagnose BV. Hoewer, these methods require time, qualified personnel and are characterized by low sensitivity and specificity. Modern diagnostic methods based on the identification of new biomarkers can significantly improve the diagnosis of BV. The analytical review discusses promising directions in the laboratory diagnosis of BV. In addition, computer algorithms (artificial intelligence) can be used to automate the diagnosis of BV based on microscopy results.
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