print ISSN: 2411-3956
Women's reproductive health and vitamin D
##common.pageHeaderLogo.altText## Actual Questions of Modern Gynecology and Perinatology

Abstract

Vitamin D deficiency is a pandemic of the 21st century. Vitamin D plays a major role in the regulation of reproductive processes in both women and men. Vitamin D receptors are present in ovarian tissue, endometrium, fallopian tubes, as well as decidual membrane and placenta. Vitamin D is involved in steroidogenesis. In the article, the role of vitamin D deficiency in the development of many gynecological problems, including polycystic ovary syndrome, endometriosis, leiomyoma of the uterus, and dysmenorrhea is investigated.

References

Amrein, K., Scherkl, M., Hoffmann, M. et al. Vitamin D deficiency 2.0: an update on the current status worldwide. //Eur J ClinNutr (2020).74, 1498–1513

Bakhru, Arvind & Mallinger, Julie & Buckanovich, Ronald & Griggs, Jennifer. (2010). Casting light on 25-hydroxyvitamin D deficiency in ovarian cancer: A study from the NHANES. //Gynecologic oncology. 119. 314-8.

Dastorani, M., Aghadavod, E., Mirhosseini, N. et al. The effects of vitamin D supplementation on metabolic profiles and gene expression of insulin and lipid metabolism in infertile polycystic ovary syndrome candidates for in vitro fertilization. //ReprodBiolEndocrinol (2018).16, 94

Gupta D, Vashi PG, Trukova K, Lis CG, Lammersfeld CA. Prevalence of serum vitamin D deficiency and insufficiency in cancer: Review of the epidemiological literature.//ExpTher Med. 2011 Mar;2(2):181-193.

Harris HR, Chavarro JE, Malspeis S, Willett WC, Missmer SA. Dairy-food, calcium, magnesium, and vitamin D intake and endometriosis: a prospective cohort study. //Am J Epidemiol. 2013 Mar 1;177(5):420-30.

Jensen, M. Vitamin D and male reproduction.// Nat Rev Endocrinol (2014).10, 175–186

Kalaitzopoulos DR, Samartzis N, Daniilidis A, Leeners B, Makieva S, Nirgianakis K, Dedes I, Metzler JM, Imesch P, Lempesis IG. Effects of vitamin D supplementation in endometriosis: a systematic review. //ReprodBiolEndocrinol. 2022 Dec 28;20(1):176.

Kalaitzopoulos, D.R., Lempesis, I., Athanasaki, F. et al. Association between vitamin D and endometriosis: a systematic review. //Hormones 19, 109–121 (2020).

Kiely, M., McCarthy, E., & Hennessy, Á. (2021). Iron, iodine and vitamin D deficiencies during pregnancy: Epidemiology, risk factors and developmental impacts.//Proceedings of the Nutrition Society,80(3), p.290-302.

Kumar A, Barki S, Raghav V, Chaturvedi A, Kumar KVSH. Correlation of Vitamin D with metabolic parameters in polycystic ovarian syndrome. //J Family Med Prim Care. 2017 Jan-Mar;6(1):115-119.

Łagowska K, Bajerska J, Jamka M. The Role of Vitamin D Oral Supplementation in Insulin Resistance in Women with Polycystic Ovary Syndrome: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. //Nutrients. 2018Nov 2;10(11):1637.

Lasco A, Catalano A, Benvenga S. Improvement of Primary Dysmenorrhea Caused by a Single Oral Dose of Vitamin D: Results of a Randomized, Double-blind, Placebo-Controlled Study. //Arch Intern Med. 2012;172(4):366–367.

Lumme J, Sebert S, Pesonen P, Piltonen T, Järvelin MR, Herzig KH, Auvinen J, Ojaniemi M, Niinimäki M. Vitamin D Levels in Women with Polycystic Ovary Syndrome: A Population-Based Study. //Nutrients. 2019 Nov 19;11(11):2831.

McGrath JJ, Burne TH, Féron F, Mackay-Sim A, Eyles DW. Developmental vitamin D deficiency and risk of schizophrenia: a 10-year update. //Schizophr Bull. 2010 Nov;36(6):1073-8.

Mitri J, Nelson J, Ruthazer R, Garganta C, Nathan DM, Hu FB, Dawson-Hughes B, Pittas AG; Diabetes Prevention Program Research Group. Plasma 25-hydroxyvitamin D and risk of metabolic syndrome: an ancillary analysis in the Diabetes Prevention Program.//Eur J ClinNutr. 2014 Mar;68(3):376-83.

Pawel Pludowski et all. Vitamin D supplementation guidelines. //The Journal of Steroid Biochemistry and Molecular Biology. Volume 175, 2018; p.125-135

Palacios C, Gonzalez L. Is vitamin D deficiency a major global public health problem? //J Steroid BiochemMol Biol. 2014 Oct;144 Pt A:138-45.

Quesada-Gomez, J.M., Bouillon, R. Is calcifediol better than cholecalciferol for vitamin D supplementation? // OsteoporosInt 29, 1697–1711 (2018).

Qin, L.-L.; Lu, F.-G.; Yang, S.-H.; Xu, H.-L.; Luo, B.-A. Does Maternal Vitamin D Deficiency Increase the Risk of Preterm Birth: A Meta-Analysis of Observational Studies. //Nutrients 2016, 8, 301.

Robert D. Simoni, Robert L. Hill, Martha Vaughan Nutritional Biochemistry and the Discovery of Vitamins: the Work of Elmer Verner McCollum //J. of Biological Chemistry. Volume 227, issue 19; 2002, p.16-18

SabriyeArslan&YaseminAkdevelioğlu The Relationship Between Female Reproductive Functions and Vitamin D.// Journal of the American College of Nutrition, (2018) 37:6, 546-551

Seyedeh Zahra Shahrokhi, Firouzeh Ghaffari, Faranak Kazerouni Role of vitamin D in female Reproduction// Clinica Chimica Acta, Volume 455, 2016, pages 33-38

Thomson, R.L., Spedding, S. and Buckley, J.D. Vitamin D in the aetiology and management of polycystic ovary syndrome. // ClinEndocrinol, (2012), 77: 343-350.

Vanni, V.S., Vigano', P., Somigliana, E. et al. Vitamin D and assisted reproduction technologies: current concepts. //ReprodBiolEndocrinol (2014). 12, 47.

Vergara D, Catherino WH, Trojano G, Tinelli A. Vitamin D: Mechanism of Action and Biological Effects in Uterine Fibroids.//Nutrients. 2021 Feb 11;13(2):597.

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Keywords

vitamin D deficiency, dysmenorrhea, endometriosis, polycystic ovary syndrome, leiomyoma D vitamini çatışmazlığı dismenoreya, endometrioz, polikistik sindrom yumurtalıqlar, leiomioma дефицит витамина D, дисменорея, эндометриоз, синдром поликистозных яичников, лейомиома