Prognostic value of macro- and micronutrient studies in arterial hypertension

Abstract

Hypertensive disorders during pregnancy are associated with an increased risk of morbidity and mortality in the mother, fetus and newborn. It is important to distinguish between pre-existing (chronic) hypertension and hypertensive conditions that develop after 20 weeks of pregnancy (preeclampsia) and usually resolve within 6 weeks after delivery. Objective of the study was to compare the levels of macronutrients (sodium, potassium, chlorine, magnesium, calcium) in the blood serum of pregnant women with chronic arterial hypertension, preeclampsia and pregnant women with normal blood pressure. Research materials and methods: To achieve this goal, we examined 100 pregnant women from 2019 to 2021. The criteria for inclusion in the study were pregnant women with high blood pressure. The obtained results were processed using modern statistical analysis software packages. The difference in values was considered statistically significant at p< 0.05. A comparative assessment of macronutrient indicators was carried out using the nonparametric Mann-Whitney criterion (U), the Wilcoxon criterion (W) and the Student criterion for independent samples (t). Statistical data analysis was carried out using the MS EXCEL, SPSS and STATISTICA software package (version 10.0). The study adds to the importance of etiological factors in the development of arterial hypertension during pregnancy and may influence prevention and treatment with mineral supplements in the prenatal period.