Immune thrombocytopenic purpura during pregnancy: features of childbirth and anesthesia (Clinical case)
Abstract
Immune thrombocytopenia is an isolated dec-rease in the number of platelets in the peripheral blood, an acquired autoimmune disease characte-rized by an increase or normalization of mega-karyocytes in the bone marrow, a shortening of the life of platelets in patients without clinical manifes-tations or factors. The onset and progression of pregnancy against the background of clinical hema-tological remission in immune thromocytopenia does not worsen the course of the disease and does not affect the prognosis and method of delivery. Exacerbation of ITP can adversely affect pregnancy and fetal viability in the form of obstetric compli-cations, which are approximately 2-3 times higher than complications in the general population.
References
Scully M, Hunt BJ, Benjamin S, et al. - Guidelines on the diagnosis and management of thrombotic thrombocytopenic purpura and other thrombotic microangiopathies. Br J Haematol. 2012;158:323-35.
Sharma R, Keyzner A, Liu J, et al. - Successful pregnancy outcome in paroxysmal nocturnal hemoglobinuria (PNH) following escalated eculizumab dosing to control breakthrough hemolysis. Leuk Res Rep. 2015; 4:36-8.
Usha Perepu, MBBS Lori Rosenstein, MD - Maternal thrombocytopenia in pregnancy. Proceedings in Obstetrics and Gynecology. 2013; 3:6.
Vesely SK, Li X, McMinn JR, et al. - Pregnancy outcomes after recovery from thrombotic thrombocytopenic purpura-hemolytic uremic syndrome. Transfusion. 2004; 44:1149-58.
Bussel J.B. Immune thrombocytopenia in pregnancy: autoimmune and alloimmune. J Reprod Immunol 1997; 37:1:35-61.
Teeling JL, Jansen-Hendriks T, Kuijpers TW, et al. Therapeutic efficacy of intravenous immunoglobulin preparations depends on the immunoglobulin G dimers: studies in experimental immune thrombocytopenia. Blood. 2001;98(4):1095.
McCrae K. Thrombocytopenia in Pregnancy. In: Michelson A, editor. Platelets. New York, NY: Elsevier; 2006.
Cines DB, Bussel JB, Liebman HA, et al. The ITP syndrome: pathogenic and clinical diversity. Blood. 2009.
McMillan R. Immune-mediated thrombocytopenias: focus on chronic immune thrombocytopenic purpura. Semin Hematol. 2007; 44(4 Suppl 5): S1.
Keywords
pregnancy
high risk group immun trombositopenik purpura
hamiləlik
yüksək risk qrupu иммунная тромбоцитопеническая пурпура
беременность
группа высокого риска.
Most read articles by the same author(s)
- J.F. Gurbanova, A.F. Amirova, N.A. Shahbazova, A.E. Huseynova, E.Sh. Salimova, The role congenital malformations of uterus at preterm births , Actual Questions of Modern Gynecology and Perinatology : Vol. 10 No. 4 (2023): Actual questions of modern gynaecology and perinatology
- J.F. Gurbanova, Kh.M. Adıgozalova, A.E. Huseynova, T.T. Kerimova, E.S. Salimova, Z.B. Abdullayeva, S.S. Veliyeva, The role of the uselessness of the scar in the uterus in premature births , Actual Questions of Modern Gynecology and Perinatology : Vol. 11 No. 3 (2024): Actual questions of modern gynaecology and perinatology
- J.F. Gurbanova, N.A. Shahbazova, Kh.M. Adigozalova-Mirzoeva, T.H. Alinaghiyeva, A.E. Huseynova, T.T. Kerimova, S.S. Veliyeva, The value of extragenital diseases in premature births , Actual Questions of Modern Gynecology and Perinatology : Vol. 11 No. 4 (2024): Actual questions of modern gynaecology and perinatology