Screening of the defi ciency of glucose-6-phosphate dehydrogenase of newborn babies
Abstract
Deficiency of glucose - 6 - phosphate dehydrogenase (G6PD) - X - linked enzyme defect, which can manifest itself as hemolysis after acute infections or ingestion
oxidants (salicylates and sulfonamides). Diagnosis is based on G6PD levels, although the test often gives a false negative result in the presence of acute hemolysis. Treatment is supportive. Since this pathology is X-linked, the complete clinical picture is observed in men and homozygous women; in heterozygous women, clinical manifestations are variable.
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