A prospective randomized cohort study was conducted, which included 86 pregnant women of the main group who received inpatient treatment for the threat of premature birth in 2023-2024 on the basis of the Research Institute of Obstetrics and
Gynecology of the Ministry of Health of Azerbaijan at various stages of pregnancy. Biochemical markers were examined to identify women at risk of spontaneous preterm birth (fetal fibronectin, insulinlike growth factor-binding protein 1, placental alphamicroglobulin-1). It was found that the value of these specific markers varied depending on the gestational
age and for each period there are more informative tests. At 22-28 weeks of pregnancy placental alphamicroglobulin-1 and insulin-like growth factorbinding protein-1 have the greatest prognostic value.
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Фаткуллин И.Ф., Ахметгалиев А.Р., Мунавирова А.А. и др. Преимущества применения диагностической экспресс-тест-системы для определения плацентарного α-микроглобулина1 в цервикальном содержимом для идентификации начавшихся угрожающих преждевременных родов // Акушерство и гинекология. – 2018. – №. 1. – С. 62 ‒ 68.
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J. C. Melchor, A. Khalil, D. Wing, E. Schleussner, D. Surbek. Prediction of preterm delivery in symptomatic women using PAMG-1, fetal fibronectin and phIGFBP-1 tests: systematic review and meta-analysis. Ultrasound Obstet Gynecol. 2018 Oct;52(4):442-451. doi: 10.1002/uog.19119. Epub 2018 Sep 4.
R. Pirjani, A. Moini, A. Almasi-Hashiani, M. F. Mojtahedi, S. Vesali, L. Hosseini, M. Sepidarkish. Placental alpha microglobulin-1 (PartoSure) test for the prediction of preterm birth: a systematic review and meta-analysis. J Matern Fetal Neonatal Med. 2021 Oct;34(20):3445-3457. doi: 10.1080/14767058.2019.1685962. Epub 2019 Nov 17.
C. Məmmədov, F. Qurbanova, F. Abbasova, H. İdrisova, K. Əliyeva. S. Qaziyeva. 22-28 həftəlik hamiləlik daxil olmaqla, vaxtından əvvəl doğuşların idarə olunmaı üzrə klinik protokol. Baki, 2014. Azərbaycan Respublikası Səhiyyə Nazirliyi.
Y. Сhekmez, G. Kiran, E. Tushtash Haberal, M. Dizdar. Use of cervicovaginal PAMG-1 protein as a predictor of delivery within seven days in pregnancies at risk of premature birth // BMC Pregnancy Childbirth. 2017 Jul 26;17(1):246. doi: 10.1186/s12884-017-1427-0.