print ISSN: 2411-3956
Features of changes in the level of vitamin D in girls with general and genital infantilism in the early reproductive period
##common.pageHeaderLogo.altText## Actual Questions of Modern Gynecology and Perinatology

Abstract

The goal of the study: To study the level of vita-min D in girls with general and genital infantilism. Material and Methods: 70 girls with general and genital infantilism were examined. Vitamin D levels were determined using “Finecare” tests in blood serum with previous work out in a centrifuge. Results: It was found that the indicator of vitamin D in girls with general infantilism (hypogonadotropic hypogonadism) was 12.02 ± 0.82 ng / ml, with genital infantilism (hypergonadotropic hypogonadism) - 15.27 ± 2.1 ng / ml, genital infantilism (normogona-dotropic hypogonadism ) - 14.29 ± 0.87 ng / ml, which corresponded to the presence of vitamin D defici-ency. The conducted pathogenetic therapy of general and genital infantilism made it possible to signifi-cantly increase the indicators of this vitamin in the blood serum.

References

Talıblı A.A., Əliyeva E.M., Axundova N.E. Cinsi yetişkənlik dövründə hiperandrogeniya sindromu olan qızlarda vitamin D və karbohidrat mübadiləsinin dəyişmə xüsusiyyətləri // Azərbaycan Tibb Jurnalı, 2020, №1, s.119-123.

Громова О.А., Торшин И.Ю., Захарова И.Н., Малявская С.И. Недостаточность витамина D и коморбидные состояния у детей 7-16 лет: интеллектуальный анализ данных // Ж. Качественная клиническая практика, 2017, №4, с.58-67.

Спиричев В.Б., Громова О.А. Витамин D и его синергиенты // Ж. «Земский Врач», 2012, №2, вып.13, с.33-38. ISSN: 2077-8392. eLIBRARY ID: 17729620

Актуальные вопросы современной гинекологии и перинатологии 08 №03/2021 43

Al-Daghri N.M., Al-Attas O.S., Alkharfy K.M. Association of VDR-gene variants with factors related to the metabolic syndrome, type 2 diabetes and vitamin D deficiency // Gene, 2014, №542, p.129-133. PMID: 24680778

Aypak C., Türed Ö., Yüce A. The association of vitamin D status with cardiometabolic risk factors, obesity and puberty in children // Eur.J.Pediatr, 2014, №173, p.367-373.

Hekimsoy Z., Dinç G., Kafesçiler S., Onur E. Vitamin D status among adults in the Aegean region of Turkey // BMC Public Health., 2010, №10, p.782.

Maghbooli Z., Hossein-Nezhad A., Shafaei A.R., Karimi F. Vitamin D status in mothers and their newborns in Iran//BMC Pregnancy Childbirth., 2007, №7, p.1.

Mirsa M., Pacaud D., Petryk A. Vitamin D deficiency in children and its management: review of current knowledge and recommendations // Pediatrics, 2008, vol.122, №2, p.398-417. doi:https://doi.org/10.1542/peds.2007-1894.

Nanri A., Foo L.H., Nakamura K., Hori A. Serum 25-hydroxyvitamin d concentrations and season-specific correlated in Japanese adults // J.Epidemiol., 2011, №21, p.346-353.

Palacios C., Gonzalez L. Is vitamin D deficiency a major global public health problem?// J.Steroid Biochem Mol.Biol., 2014, №144, p.138-145.

Tabrizi R., Moosazadeh M., Akbari M., Dabbaghmanesh M.H. High Prevalence of Vitamin D Deficiency among Iranian Population. A Systematic Review and Meta-Analysis // Iran.J.Med.Sci., 2018, №43, p.125-139.

Torkaman M., Abolghasem H., Amirsalari S., Beiraghdar F. Compaison of the Vitamin D Status of Children Younger and Older Than 2 Years in Tehran: Are Supplements Really Necessary?// Int J. Endocrin.Metab., 2016, №14, p.34676. 13. Zhao Y., Long W., Du C., Yang H., Wa S. Prevalence of vitamin D deficiency in girls with idiopathic central precocious puberty // Front Med., 2018, №12, р.174-181.

PDF (Azərbaycanca)
PDF (Azərbaycanca)

Keywords

general infantilism
genital infantilism
hypogonadotropic hypogonadism
hypergonadotropic hypogonadism
normogonadotropic hypogonadismnormogonadotropic hypogonadism
vitamin D deficiency ümumi infantilizm
genital infantilizm
hipoqonadotrop hipoqonadizm
hiperqonadotrop hipoqonadizm
normoqonadotrop hipoqonadizm
D vitamini çatışmazlığı общий инфантилизм
генитальный инфантилизм
гипогонадотропный гипогонадизм
гипергонадотропный гипогонадизм
нормогонадотропный гипогонадизм
дефицит витамина Д